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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRK7 All Species: 12.66
Human Site: S547 Identified Species: 21.43
UniProt: Q8WTQ7 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8WTQ7 NP_631948.1 553 62212 S547 E E G N S S K S G V C L L L _
Chimpanzee Pan troglodytes XP_526333 553 62171 S547 G E G N S S K S G V C L L L _
Rhesus Macaque Macaca mulatta XP_001112570 553 62224 S547 G E G N S S K S G V C L L L _
Dog Lupus familis XP_542813 553 62196 S547 G D G N S S K S G V C L L L _
Cat Felis silvestris
Mouse Mus musculus Q8VEB1 590 67714 Q541 S P D L N R S Q P P E P P K K
Rat Rattus norvegicus Q62833 590 67764 Q541 S P D L N R S Q P P E P P K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514822 565 64022 P548 P D D M R D G P G E D E T A S
Chicken Gallus gallus XP_426681 551 62925 A543 G Y A N G G E A K S G V C L L
Frog Xenopus laevis NP_001131051 551 62674 K544 G G G N S G E K S G V C S I L
Zebra Danio Brachydanio rerio NP_001027011 549 62214 K542 G G S D D D K K S G T C T L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P32866 714 80668 A669 T P D L Q I N A A P E P D K A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q09537 642 73759 D572 V M W N L R P D G I N M D E R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42818 465 52569
Baker's Yeast Sacchar. cerevisiae P11792 824 91793 M805 M N N S H S Q M D F D G D Q H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 96.9 85.7 N.A. 41.8 42.2 N.A. 47.9 72.8 68.7 60.2 N.A. 38.2 N.A. 39.4 N.A.
Protein Similarity: 100 99.4 98 92.7 N.A. 60.6 60.6 N.A. 65.8 84.2 82.8 75.9 N.A. 54.3 N.A. 57.6 N.A.
P-Site Identity: 100 92.8 92.8 85.7 N.A. 0 0 N.A. 6.6 13.3 20 13.3 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 92.8 92.8 92.8 N.A. 6.6 6.6 N.A. 13.3 33.3 33.3 20 N.A. 6.6 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.3 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. 45.3 38.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 15 8 0 0 0 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 29 15 8 0 0 % C
% Asp: 0 15 29 8 8 15 0 8 8 0 15 0 22 0 0 % D
% Glu: 8 22 0 0 0 0 15 0 0 8 22 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 43 15 36 0 8 15 8 0 43 15 8 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 0 8 0 0 0 8 0 % I
% Lys: 0 0 0 0 0 0 36 15 8 0 0 0 0 22 15 % K
% Leu: 0 0 0 22 8 0 0 0 0 0 0 29 29 43 22 % L
% Met: 8 8 0 8 0 0 0 8 0 0 0 8 0 0 0 % M
% Asn: 0 8 8 50 15 0 8 0 0 0 8 0 0 0 0 % N
% Pro: 8 22 0 0 0 0 8 8 15 22 0 22 15 0 0 % P
% Gln: 0 0 0 0 8 0 8 15 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 0 8 22 0 0 0 0 0 0 0 0 8 % R
% Ser: 15 0 8 8 36 36 15 29 15 8 0 0 8 0 8 % S
% Thr: 8 0 0 0 0 0 0 0 0 0 8 0 15 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 29 8 8 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29 % _